USMLE® Step 2 CK · chapter GI

Gastroenterology: USMLE® Step 2 CK topics

26 topics. Each one opens a review page with its guideline basis and key clinical sections, then links the QuestionBank questions, ChartWalk flowchart, FlashCards and ImageBank plates that share its code.

1. Abdominal wall hernias — types & operative timing

   GI-HERN-0112 questions · Review Book p. 298 · 2018 HerniaSurge International Groin Hernia Guidelines

2. Acute liver failure, HCC & liver mass workup

   GI-LIV-0233 questions · Review Book p. 320 · ACG Acute Liver Failure Guidelines (2023); AASLD HCC Practice Guidance (2023; Critical Update 2025)

3. Acute mesenteric ischemia & ischemic colitis

   GI-ISCH-0126 questions · Review Book p. 303 · European Society for Vascular Surgery (ESVS) 2025 Clinical Practice Guidelines on the Management of Diseases of the Mesenteric and Renal Arteries and Veins; Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery (2022)

4. Acute pancreatitis — severity, complications & ERCP timing

   GI-PANC-0144 questions · Review Book p. 305 · 2024 ACG Acute Pancreatitis; 2012 Revised Atlanta Classification

5. Anorectal disorders — hemorrhoids to rectal prolapse

   GI-ANOR-013 questions · Review Book p. 297 · 2021 ACG Clinical Guidelines: Management of Benign Anorectal Disorders; ASCRS hemorrhoid (2024) and anal fissure (2023) guidelines

6. Appendicitis — diagnosis across populations

   GI-APP-0124 questions · Review Book p. 300 · 2025 WSES Jerusalem Guidelines (published 2026); 2024 IDSA Diagnostic Imaging Guideline

7. Ascending cholangitis & cholangiocarcinoma

   GI-BIL-0225 questions · Review Book p. 310 · 2018 Tokyo Guidelines (Acute Cholangitis); 2022 AASLD PSC & Cholangiocarcinoma Guidance

8. Celiac disease & malabsorptive syndromes

   GI-CEL-0124 questions · Review Book p. 288 · American College of Gastroenterology Guidelines Update: Diagnosis and Management of Celiac Disease (2023)

9. Cholelithiasis & cholecystitis — decision ladder

   GI-BIL-0124 questions · Review Book p. 308 · Tokyo Guidelines 2018

10. Chronic liver disease etiologies beyond viral hepatitis

    GI-LIV-0160 questions · Review Book p. 318 · 2023 AASLD MASLD/metabolic dysfunction-associated steatohepatitis (MASH) Practice Guidance; 2022 AASLD Wilson Disease Practice Guidance

11. Chronic pancreatitis & pancreatic cancer

    GI-PANC-0224 questions · Review Book p. 307 · 2020 ACG Clinical Guideline: Chronic Pancreatitis

12. Cirrhosis — ascites & spontaneous bacterial peritonitis

    GI-CIRR-0126 questions · Review Book p. 314 · AASLD Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome Guidance (2021)

13. Diverticular disease, polyps & colorectal cancer

    GI-COLON-0134 questions · Review Book p. 294 · 2026 ASCRS & ACG Colonic Diverticulitis Guidelines; 2021 USPSTF CRC Screening

14. Dysphagia, achalasia & esophageal perforation

    GI-ESO-0232 questions · Review Book p. 284 · ACG Achalasia guideline (2020)

15. GERD, Barrett esophagus & esophageal cancer

    GI-ESO-0115 questions · Review Book p. 282 · ACG GERD guideline (2022)

16. Hepatic encephalopathy, portal hypertension & hepatorenal syndrome

    GI-CIRR-0235 questions · Review Book p. 316 · 2026 ACG Clinical Guideline: Hepatic Encephalopathy; 2024 ADQI-ICA acute kidney injury in cirrhosis consensus

17. Hepatitis B serology & viral hepatitis interpretation

    GI-HEP-0128 questions · Review Book p. 312 · AASLD/IDSA Practice Guideline on Treatment of Chronic Hepatitis B (2025; published 2026); AASLD Hepatitis B Guidance (2018, remaining topics)

18. IBD treatment ladders & surgical indications

    GI-IBD-0221 questions · Review Book p. 291 · ACG Clinical Guideline Update: Ulcerative Colitis in Adults (2025); ACG Clinical Guideline: Management of Crohn’s Disease in Adults (2025)

19. Infectious diarrhea, C difficile & functional bowel disease

    GI-FUNC-0142 questions · Review Book p. 292 · SHEA/IDSA Clinical Practice Guidelines for Clostridioides difficile Infection (2017; 2021 focused update); IDSA Infectious Diarrhea (2017)

20. Other & rare GI/hepatobiliary entities

    GI-OTH-0117 questions · Review Book p. 324 · NCCN Neuroendocrine and Adrenal Tumors Guidelines (2025)

21. Pediatric GI & hepatobiliary emergencies

    GI-PEDS-0136 questions · Review Book p. 322 · 2022 AAP Hyperbilirubinemia (≥35 wk GA); 2025 AAP Biliary Atresia Clinical Report

22. Peptic ulcer disease, gastric cancer & related tumors

    GI-GAST-0147 questions · Review Book p. 286 · ACG Clinical Guideline: Treatment of Helicobacter pylori Infection (2024)

23. Small & large bowel obstruction, ileus & volvulus

    GI-OBST-0120 questions · Review Book p. 301 · 2012 EAST Small Bowel Obstruction

24. Ulcerative colitis vs Crohn disease — diagnosis

    GI-IBD-0131 questions · Review Book p. 289 · ACG Clinical Guideline Update: Ulcerative Colitis in Adults (2025); ACG Clinical Guideline: Management of Crohn’s Disease in Adults (2025)

25. Upper vs lower GI bleeding — localization & triage

    GI-BLEED-0115 questions · Review Book p. 278 · ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding (2021); Management of Patients With Acute Lower Gastrointestinal Bleeding: An Updated ACG Guideline (2023)

26. Variceal vs non-variceal upper GI bleed management

    GI-BLEED-0215 questions · Review Book p. 280 · ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding (2021); Baveno VII – Renewing consensus in portal hypertension (2022)

Written and clinically reviewed by TheCodexes.com (editorial policy). Guideline citations are the primary sources each topic follows.